Role of Extracellular Vesicles in Breast Cancer, its Diagnostics and Treatment
Kratka vsebina
While the risk factors of breast cancer have been extensively studied and recorded, the understanding of the microscopic and nanoscopic mechanisms causing the disease is not yet satisfactory. Recent research in cell biology points to sub-micron sized extracellular vesicles (EVs) which are by now acknowledged to deliver cargo to cells and thereby mediate interaction between them. Investigation of EVs is challenging, as presently there are no golden standard methods for their isolation from bodily fluids or tissues, and their characterization. They are tiny (nano-sized) particles with dynamic identity that require development of new technologically advanced methods. This contribution presents a brief survey of the evidences on various facts that are being collected on breast cancer EVs.