Extracellular Vesicles in Bovine Colostrum and Milk

Cow (bovine) colostrum (milk on the day after the calf birth) and milk (milked on the days 3 and 6 after the parturition) extracellular particles (EPs) were investigated by in-terferometric light microscopy (ILM). Colostrum and milk samples were taken from a Limousin cow on days 1, 3 and 6 after the parturition. Number density n and hydrody-namic diameter Dh of EPs were measured. Higher n was found in skimmed samples compared to the whole samples on days 1, 3 and 6 after the parturition, however the differences were statistically significant only on days 1 and 3 after the parturition. The sizes of the particles (Dh) were within the error of the method, and the differences be-tween the skimmed and whole samples were statistically significant only on the day 3.